cAMP Gentaur ADRA2A Receptor Cell Line

Description cAMP Gentaur Cells are cell lines stably co-expressing tag-free GPCRs and cAMP Gentaur Biosensor to monitor G-protein modulation by cAMP release. Each vial of cAMP Gentaur ADRA2A Receptor Cell Line contains U2OS cells stably expressing the following constructs: Human α2A-adrenoceptor with no tag cAMP Gentaur Biosensor (Green Fluorescence) cAMP Gentaur ADRA2A Receptor Cell Line allows to assay compounds analyzing the G-Protein signaling pathway by cAMP involving receptor activation. When an agonist binds to ADRA2A, a G protein is activated. This activation triggers a cellular response mediated by changes in cAMP levels. The ADRA2A Receptor Cell Line leads to an increase in green fluorescence intensity of the cAMP biosensor. Thus, receptor activity can be easily quantified in living cells in a dose-dependent manner by measuring fluorescence emission with a microplate reader.